Endocrine Abstracts

The classic clinic manifestation of primary hyperparathyroidism (PHPT) is osteitis fibrosa cystica, a severe skeletal disease characterized by brown tumors, bone cysts and deformities, due to extremely elevated bone resorption elicited by continuously high parathyroid hormone (PTH) levels. In cardiovascular system there may be shortened QT interval, deposition of calcium in heart valves, coronary arteries, and myocardial fibers. Here, we report a case with PHPT, who have anore...

Introduction: Aortic elastic properties and aortic stiffness are important determinants of increased cardiovascular morbidity and mortality in different diseases. We aimed to investigate the aortic function and to evaluate the relationship between aortic stiffness and systolic and diastolic functions of the left ventricle in patients with Cushing’s disease (CD).Material and method: Fourteen women and one man with newly diagnosed CD, and 17 control c...

Objective: To verify whether tissue Doppler imaging (TDI) could contribute to a better understanding of the natural history of cardiomyopathy in active Cushing’s disease (CD), through its enhanced sensitivity to diastolic dysfunction, and identifying preliminary regional signs of systolic dysfunction, before the appearance of clinical symptoms of cardiac pathologies.Methods: Eleven women with newly diagnosed CD, and 15 control cases, purposely match...